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Fig. 1 | Infectious Agents and Cancer

Fig. 1

From: Novel insights into immune-gut microbiota interactions in colorectal cancer: a Mendelian randomization study

Fig. 1

Study flowchart. Step 1A represents the causal effects of immune cells on CRC. Step 1B represents the bidirectional causal effects between immune cells and CRC. Step 2A represents the causal effects of gut microbiota on CRC. Step 2B represents the bidirectional causal effects between gut microbiota and CRC. Step 3 represents the mediation analysis of gut microbiota in the pathway from immune cells to CRC: path a indicates the causal effect of immune cells on gut microbiota; path b indicates the causal effect of gut microbiota on CRC; and path c represents the total effect of immune cells on CRC

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