Table 2 Demographic and clinical characteristics of HIV infected and HIV-negative women with CIN3

Median age (IQR)

37 (34–41)

35 (32–43)

0.382

Ethnicity

 African

6 (14%)

5 (13%)

0.131

 Mixed Ancestry

3 (7%)

2 (5%)

 Unknown

34 (79%)

32 (82%)

–

Comorbidities

 Yes

16 (37%)

18 (46%)

0.45

 No

13 (30%)

14 (36%)

 Unknown

14 (33%)

7 (18%)

–

Family history of cancer

 Yes

1 (2%)

7 (18%)

0.715

 No

1 (2%)

4 (10%)

 Unknown

41 (98%)

28 (72%)

–

Smoking history

 Yes

5 (12%)

20 (51%)

 < 0.0001*

 No

33 (52%)

19 (49%)

 Unknown

5 (12%)

0

–

Alcohol history

 Yes

6 (14%)

6 (15%)

0.784

 No

11 (26%)

9 (23%)

 Unknown

26 (60%)

24 (62%)

–

BMI

 Average 20–24

11 (26%)

5 (13%)

0.243

 Above average 25–29

1 (2%)

2 (5%)

 Unknown

31 (72%)

32 (82%)

–

Menarche

 10–15 years

6 (14%)

12 (31%)

0.119

 16–20 years

4 (9%)

1 (2%)

 > 20 years

0

1 (2%)

 Unknown

33 (77%)

25 (65%)

–

Menstruation irregularity

 Monthly

15 (35%)

3 (8%)

0.005*

 Skipped for 1–3 months

1 (2%)

5 (13%)

 Amenorrhea

8 (19%)

21 (53%)

 Menopause

6 (14%)

3 (8%)

 Unknown

13 (30%)

7 (18%)

–

Type of contraceptive

 Oral

0

1 (2%)

0.019*

 Implant

2 (5%)

5 (13%)

 Injectable

18 (42%)

19 (49%)

 Tubal ligation

4 (9%)

5 (13%)

 None

15 (35%)

2 (5%)

 Unknown

4 (9%)

7 (18%)

–

Duration of contraceptive use

 1–5 years

2 (5%)

1 (2%)

0.902

 6–10 years

2 (5%)

1 (2%)

 > 10 years

3 (7%)

3 (8%)

 Unknown

36 (83%)

35 (88%)

–

Parity

 Primiparity

5 (12%)

2 (5%)

0.179

 Multiparity

38 (88%)

37 (95%)

Age at first conception

 15–20 years

6 (14%)

5 (13%)

0.186

 21–25 years

4 (9%)

4 (10%)

 26–30 years

0

2 (5%)

 Unknown

33 (77%)

28 (72%)

–

Viral load (copies/ml), n (%)

 Less than detectable

19 (44%)

–

 < 200

16 (37%)

 200–999

3 (7%)

 > 1000

5 (12%)

CD4 count (cells/mm³), n (%)

 < 200

8 (19%)

–

 200–500

12 (28%)

 > 500

10 (23%)

 Unknown

13 (30%)