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Table 1 Comparison between patients who underwent surgery and developed postoperative complications versus those who did not (N = 339)

From: Optimizing timing for elective surgery in cancer patients following COVID-19 infection; a post-pandemic analysis

Variable

Level

Total Cohort

N (%)

Postoperative Complications = No (N = 261, 77%)

Postoperative Complications = Yes (N = 78, 23%)

P value

Frequency

(%)

Frequency

(%)

Age

Mean

51.5

51.3

52

0.72

Median

52

51

51.5

SD

14.56

14.6

14.4

Range (Max - Min)

69 (89 − 20)

69 (89 − 20)

66 (86 − 20)

Sex

Female

201 (59.29%)

154

76.62%

47

23.38%

0.84

Male

138 (40.71%)

107

77.54%

31

22.46%

Smoking Status

EX

28 (8.26%)

21

75.00%

7

25.00%

0.93

No

211 (62.24%)

162

76.78%

49

23.22%

Yes

100 (29.5%)

78

78.00%

22

22.00%

Preoperative Comorbidity

No

149 (43.95%)

119

79.87%

30

20.13%

0.27

Yes

190 (56.05%)

142

74.74%

48

25.26%

Number of Comorbidity

1

87 (25.66%)

64

73.56%

23

26.44%

0.56

2

59 (17.4%)

47

79.66%

12

20.34%

3

33 (9.73%)

24

72.73%

9

27.27%

> 3

11 (3.24%)

7

63.64%

4

36.36%

Type of Comorbidity

Hypertension

No

227 (66.96%)

175

77.09%

52

22.91%

0.9

Yes

112 (33.04%)

86

76.79%

26

23.21%

Diabetes

No

270 (79.65%)

209

77.41%

61

22.59%

0.72

Yes

69 (20.35%)

52

75.36%

17

24.64%

Cardiac Comorbidity

No

313 (92.33%)

242

77.32%

71

22.68%

0.62

Yes

26 (7.67%)

19

73.08%

7

26.92%

Pulmonary Comorbidity

No

323 (95.28%)

249

77.09%

74

22.91%

0.85

Yes

16 (4.72%)

12

75.00%

4

25.00%

Renal Comorbidity

No

327 (96.46%)

255

77.98%

72

22.02%

0.35

Yes

12 (3.54%)

6

50.00%

6

50.00%

Other

No

225 (66.37%)

177

78.67%

48

21.33%

0.3

Yes

114 (33.63%)

84

73.68%

30

26.32%

Type of cancer

Breast Cancer

104 (30.68%)

85

81.73%

19

18.27%

0.06

Connective tumors

17 (5.01%)

10

58.82%

7

41.18%

GI cancer

66 (19.47%)

51

77.27%

15

22.73%

Gynecology

15 (4.42%)

9

60.00%

6

40.00%

Head & Neck

24 (7.08%)

20

83.33%

4

16.67%

Hematology

49 (14.45%)

36

73.47%

13

26.53%

Neurosurgery

12 (3.54%)

6

50.00%

6

50.00%

Urology

41 (12.09%)

36

87.80%

5

12.20%

Other

11 (3.24%)

8

72.73%

3

27.27%

Metastatic Disease

No

264 (77.88%)

203

76.89%

61

23.11%

0.94

Yes

75 (22.12%)

58

77.33%

17

22.67%

Neoadjuvant Therapy

No

166 (48.97%)

133

80.12%

33

19.88%

0.37

Yes

173 (51.03%)

128

73.99%

45

26.01%

Type of Neoadjuvant Therapy

RTx

11 (3.24%)

7

63.64%

4

36.36%

0.39

CTx

124 (36.58%)

91

73.39%

33

26.61%

CRTx

38 (11.21%)

30

78.95%

8

21.05%

Vaccine

No

183 (53.98%)

143

78.14%

40

21.86%

0.59

Yes

156 (46.02%)

118

75.64%

38

24.36%

COVID Waves

Wave 1

134 (39.53%)

111

42.50%

23

39.50%

0.039

Wave 2

205 (60.47%)

150

57.50%

55

60.50%

Symptomatic

No

152 (44.84%)

125

82.24%

27

17.76%

0.039

Yes

187 (55.16%)

136

72.73%

51

27.27%

Delay Periods (Between COVID-19 and Surgery)

Less than 2 weeks

56.0 (16.5%)

29

11.1%

27

34.6%

< 0.001

From 2 to 3 weeks

49.0 (14.5%)

44

16.9%

5

6.4%

More than 3 weeks

234.0 (69.0%)

188

72%

46

59%

ASA

1

12 (3.54%)

10

83.33%

2

16.67%

0.27

2

301 (88.79%)

231

76.74%

70

23.26%

3

23 (6.78%)

19

82.61%

4

17.39%

4

3 (0.88%)

1

33.33%

2

66.67%

Grade of surgery

Major

156 (46.02%)

113

72.44%

43

27.56%

0.18

Medium

97 (28.61%)

78

80.41%

19

19.59%

Minor

86 (25.37%)

70

81.40%

16

18.60%

Length Of Stay (Days)

Mean (SD)

3.3 (7.8)

2.1 (3.6)

7.3 (14.1)

< 0.0001

Range

0–99

0–37

0–99