Fig. 8
From: Potential mechanism of circKIAA1429 accelerating the progression of hepatocellular carcinoma

The effect of circKIAA1429/GLIS2/NAP1L3 on HCC progression. circKIAA1429 directly interacts with SETD1A to inhibit the enrichment of SETD1A and H3K4me3/H3K27me3 on the GLIS2 or NAP1L3 promoter, resulting in a decrease in GLIS2 expression and an increase in NAP1L3 expression, ultimately accelerating the progression of HCC