Fig. 4
From: Potential mechanism of circKIAA1429 accelerating the progression of hepatocellular carcinoma
circKIAA1429 directly interacts with SETD1A to inhibit the enrichment of H3K27me3 on the NAP1L3 promoter, leading to an increase in NAP1L3 expression. A: The enrichment of SETD1A and H3K4me3 on NAP1L3 promoter was analysis by ChIP. B-E: NAP1L3 expression in cells was detected by RT-qPCR and western blot. The cell experiments were repeated 3 times independently. The data are expressed as mean ± standard deviation. The data in panels B-C were analyzed by one-way ANOVA, and data in panels A, D-E were analyzed by two-way ANOVA, followed by Tukey’s multiple comparisons test. **P < 0.01