Fig. 4
From: Precision therapeutic targets for HPV-positive cancers: an overview and new insights
TFs interacted with the LCR. Multiple TFs are proven or putative to interact with LCR of HPV16 and HPV18. YY-1, NF-1, NF-κb, SOX2, TEF-1, AP-1 and Oct-1 are proven to interact with LCR of HPV 16, while MYC and FOXA1 have putative interaction. For HPV 18, role of NF-1 and Oct-1 are proved and those of FOXA1, GATA3, MYC are putative