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Table 3 The performance of HPV&TCT co-testing and HPV integration test for identifying residual/recurrent CIN

From: Risk of residual/recurrent cervical diseases in HPV-positive women post-conization depends on HPV integration status

 

HPV & TCT co-testing

% (95% CI)

HPV integration test

% (95% CI)

Sensitivity

91.67% (60.0-99.5%)

33.3% (11.2-64.5%)

Specificity

14.8% (7.3-29.5%)

90.2% (79.1-96.0%)

PPV

17.5% (9.4-30.9%)

40.0% (13.7-72.6%)

NPV

90.0% (54.11-99.48%)

87.3% (76.0-94.0%)

  1. Footnotes: Thresholds: cytology ≥ LSIL, or cytological ASC-US with any HR-HPV (+), or cytologically normal (NILM) but HPV-16/-18 (+); HPV integration (+)
  2. Abbreviations: 95% CI, 95% confidence interval; PPV, positive predictive value; NPV, negative predictive values
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Infectious Agents and Cancer

ISSN: 1750-9378

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