Fig. 4

miR-3191 promotes HCC cells proliferation and metastasis (A) Relative expression of miR-3191 in Huh7 and Hep3B cells after infection of miR-33,191 overexpression virus or control virus (n = 3). (B) Relative proliferation curve of Huh7 and Hep3B treated with miR-3191 mimic and control cells at 0, 24, 48, 72 and 96 h (n = 4). (C) Relative proliferation of Huh7 and Hep3B treated with miR-3191 mimic and control cells (n = 3). (D) EdU assay of Huh7/Hep3B miR‑3191 mimic and control cells (n = 3). Scale bar = 25 μm. (E) Transwell migration of Huh7 and Hep3B treated with miR-3191 mimic and control cells (n = 3). Scale bar = 100 μm. (F) Transwell invasion of Huh7 and Hep3B treated with miR-3191 mimic and control cells (n = 3). Scale bar = 100 μm. (G) Western bolt analysis of E-cadherin and N-cadherin protein expression in Huh7 and Hep3B treated with miR-3191 mimic and control cells