Table 3 Reported Spearman correlation coefficient for DNA methylation levels in urine or cervicovaginal swab self-samples as compared to clinician-collected cervical scrapes and in urine as compared to cervicovaginal swabs
Marker | Sample | Comparator | Spearman Co. | Significance | Study |
|---|---|---|---|---|---|
ASCL1 | Urine | LBC | 0.42 | p < 0.001 | Van den Helder, 2022 |
SST | Urine | LBC | 0.46 | p < 0.001 | Van den Helder, 2022 |
GHSR | Urine | LBC | 0.48 | p < 0.001 | Van den Helder, 2022 |
ZIC1 | Urine | LBC | 0.5 | p < 0.001 | Van den Helder, 2022 |
PRDM14 | Urine | LBC | 0.508 | Snoek, 2019 | |
LHX8 | Urine | LBC | 0.52 | p < 0.001 | Van den Helder, 2022 |
GHSR | Urine | LBC | 0.543 | Snoek, 2019 | |
LHX8 | Swab | LBC | 0.55 | Verhoef, 2023 | |
ASCL1 | Swab | LBC | 0.56 | p < 0.001 | Van den Helder, 2022 |
ASCL1 | Swab | LBC | 0.563 | Verhoef, 2023 | |
ZIC1 | Swab | LBC | 0.59 | p < 0.001 | Van den Helder, 2022 |
SST | Swab | LBC | 0.6 | p < 0.001 | Van den Helder, 2022 |
GHSR | Swab | LBC | 0.61 | p < 0.001 | Van den Helder, 2022 |
ZIC1 | Urine | LBC | 0.613 | Snoek, 2019 | |
SST | Urine | LBC | 0.621 | Snoek, 2019 | |
LHX8 | Swab | LBC | 0.63 | p < 0.001 | Van den Helder, 2022 |
FAM19A4 | Urine | LBC | 0.674 | Snoek, 2019 | |
PHACTR3 | Urine | LBC | 0.717 | Snoek, 2019 | |
SST | Urine | Swab | 0.59 | p < 0.001 | Van den Helder, 2022 |
ASCL1 | Urine | Swab | 0.61 | p < 0.001 | Van den Helder, 2022 |
ZIC1 | Urine | Swab | 0.61 | p < 0.001 | Van den Helder, 2022 |
LHX8 | Urine | Swab | 0.62 | p < 0.001 | Van den Helder, 2022 |
GHSR | Urine | Swab | 0.65 | p < 0.001 | Van den Helder, 2022 |