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Table 1 Clinicopathological characteristics of patients with PC in cohorts 1, 2, and 3

From: Highly sensitive deep panel sequencing of 27 HPV genotypes in prostate cancer biopsies results in very low detection rates and indicates that HPV is not a major etiological driver of this malignancy

Characteristic

Cohort 1

Cohort 2

Cohort 3

   Malignant samples, N

83

16

132

   Age (years) at RP, median (range)

65 (45–76)

N/A

64 (50–76)

Preoperative PSA (ng/ml)

   

   ≤ 10, N (%)

39 (47.0%)

N/A

42 (31.8%)

   > 10, N (%)

39 (47.0%)

N/A

90 (68.2%)

   Unknown, N (%)

5 (6.0%)

N/A

0 (0.0%)

ISUP Grade Group

   

   ≤ 3, N (%)

63 (75.9%)

9 (56.2%)

110 (83.3%)

   > 3, N (%)

20 (24.1%)

7 (43.7%)

22 (16.7%)

Pathological T-stage

   

   T2, N (%)

51 (61.4%)

4 (25.0%)

85 (64.4%)

   T3, N (%)

31 (37.4)

10 (62.5%)

47 (35.6%)

   Unknown/T4, N (%)

1 (1.2%)

2 (12.5%)

0 (0.0%)

Biochemical recurrence (BCR) status

   

   BCR, N (%)

28 (33.7%)

6 (37.5%)

70 (53.0%)

   BCR-free, N (%)

31 (63.9%)

10 (62.5%)

62 (47.0%)

   Unknown, N (%)

2 (2.4%)

0 (0.0%)

0 (0.0%)

Total follow-up in months, median (range)

52.4 (17.6-178.9)

N/A

147.7 (6.0-267.6)