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Fig. 5 | Infectious Agents and Cancer

Fig. 5

From: Highly sensitive deep panel sequencing of 27 HPV genotypes in prostate cancer biopsies results in very low detection rates and indicates that HPV is not a major etiological driver of this malignancy

Fig. 5

A) Coverage, i.e., the average number of reference reads across all prostate tissue samples included in cohort 3. AN, Adjacent normal. BPH, benign prostatic hyperplasia. PC, prostate cancer. B) Normalized reads, i.e., the number of reads per 10,000 reference reads, of the HPV16, HPV70, and HPV73 amplicons for all the samples divided into HPV-positive (red) and HPV-negative (blue) groups. The dotted lines connect amplicons of individual samples. Horizontal line: cut-off for HPV positivity (two amplicons need to be above this line for a sample to be rendered HPV positive)

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