Table 3 Characteristics of studies included in this review
From: The role of helminths and their antigens in cancer therapy: insights from cell line models
Cell line | origin | Cell type | Helminth | Ags | Year | Country | Reference |
|---|---|---|---|---|---|---|---|
HepG2 SK-OV-3 A549 | Liver Ascites Lung | Hepatocellular ovarian Epithelial | Trichinella spiralis | ESP* | 2022 | Thailand | [12] |
Panc02TA3/Ha | Pancreasbreast | syngeneic pancreatic tumor syngeneic mammary adenocarcinoma | Echinococcus granulosus | Mucin-like peptides (MUC6*) Tn antigen | 2013 | Uruguay | [15] |
CCA* | bile duct | Cholangiocarcinoma | O. viverrini | Metacercariae | 2020 | Thailand | [33] |
CCA*( HuCCT1) | The epithelium of the biliary tract | Cholangiocarcinoma | Clonorchis sinensis | Excretory-secretory products | 2017 | Korea | [34] |
MPSIEC* | Intestinal | Epithelial | Fasciola hepatica | Tegument and Somatic FhNEJ* | 2022 | Uruguay | [35] |
Human HCC* HepG2 | Liver | Hepatcellular carcinoma | Echinococcus granulosus | Echinococcus granulosus PSCs*from the liver hydatid cysts | 2022 | China | [36] |
A375 | Skin | Melanoma cell | Echinococcus granulosus | 1.Fertile and Infertile (Hydatid cyst fluid) 2. Fertile (containing protoscoleces (PSCs*) and infertile (without PSCs*) liver hydatid cyst | 2022 | Iran | [37] |
CCA-OF | bile duct | Cholangiocarcinoma | Opisthorchis felineus | O. felineus metacercariae | 2021 | vimentin | [38] |
JAWSII | Bone marrow | an immortalized immature DC line | Opisthorchis felineus | Extract hemozoin from Opisthorchis felineus | 2019 | China | [39] |
CCA*(HuCCT1)H69 | bile duct | Cholangiocarcinoma | Clonorchis sinensis | Excretory-secretory products (ESPs*) | 2019 | Korea | [40] |
MCF-7T47D MDA-MB-231FaDu HeLa SCC15 CJMNFF | Breast BreastBreast Pharynxcervicaltongue skinforeskin | breast adenocarcinomabreast ductal carcinoma | Echinococcus granulosus | Oncosphere (EgKI-1*) | 2019 | Australia | [41] |
RBE-GRNPLC-GRN | liver | CholangicarcinomaHepatocellular carcinoma | C. Sinensis | The mRNA sequence annotated with granulin (CsGRN*) | 2017 | China | [42] |
HuCCT-1Cho-CK Choi-CK | bile duct | Cholangiocarcinoma | Clonorchis sinensis | Excretory–secretory products | 2017 |  Korea | [43] |
KKU-M214 H-69 | liver lung | Cholangiocarcinoma cholangiocyte | O. viverrini | Excretory-secretory products | 2014 | Thailand | [44] |
CCA* (HuCCT1) | bile duct | Cholangiocarcinoma | Clonorchis sinensis | Excretory–secretory products let-7a let-7i miR-16 miR-24 miR-31 miR-93 miR-95 miR-124a miR-136 miR-153 miR-181d miR-185 miR-195 miR-199a-3p miR-342-5p miR-373 | 2014 | Korea | [45] |
HuCCT1 | Epithelial bile duct | Cholangiocarcinoma | C. sinensis | Excretory–secretory products (metacercariae) | 2014 | Korea | [46] |
NCI-H209/An1L929 | Bone marrowAdipose | Lung small cell carcinomafibroblasts(control) | Echinococcus granulosus | sera from patients with hydatid cysts | 2013 | Turkey | [47] |
NIH-3T3  MMNK1 | whole mouse embryos Fetal liver | murine fibroblasts     Cholangiocyte | O. viverrini | Crude ESP* | 2012 | Thailand | [48] |
HCT116 | colon | colon cancer cell | Heligmosomoides polygyrus | excretory-secretory | 2020 | UK | [49] |
AGS HT-29Â Caco 2 | Stomach Colon | gastric cancer colon adenocarcinoma colon adenocarcinoma | Toxocara canis | excretory-secretory troponin protein | 2022 | IRAN | [50] |
4T1Â | Mammary gland | Epithelial | Echinococcus granulosus | Antigen B | 2019 | Iran | [51] |