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Table 4 Stratification analyses of rs1859168 and rs7158663 genotypes among NPC patients

From: Genetic variants of LncRNAs HOTTIP and MEG3 influence nasopharyngeal carcinoma susceptibility and clinicopathologic characteristics in the Southern Chinese population

Characteristics

HOTTIP rs1859168 Genotype n (%)

MEG3 rs7158663 Genotype n (%)

AA

AC + CC

p-value

OR (95% CI)

GG

GA + AA

p-value value

OR (95% CI)

Gender

        

Male

34(22.52)

117(77.48)

0.757

1.133(0.513,2.504)

68(45.03)

83(54.97)

0.443

1.294(0.670,2.699)

Female

10(20.41)

39(79.59)

  

19(38.78)

30(61.22)

  

Age, years

        

≤ 50

16(19.05)

68(80.95)

0.391

1.352(0.678,2.699)

39(46.43)

45(53.57)

0.477

1.228(0.697,2.162)

> 50

28(24.14)

88(75.86)

  

48(41.38)

68(58.62)

  

EBV-DNA

        

Positive

32(19.88)

129(80.12)

0.141

1.792(0.819,3.918)

73(45.34)

88(54.66)

0.286

1.481(0.718,3.056)

Negative

12(30.77)

27(69.23)

  

14(35.90)

25(64.10)

  

Nationality

        

Han

25(23.15)

83(76.85)

0.671

1.157(0.590,2.271)

50(46.30)

58(53.70)

0.387

1.281(0.730,2.250)

Zhuang

19(20.65)

73(79.35)

  

37((40.22)

55(59.78)

  

Smoking status

        

Smoker

9(16.67)

45(83.33)

0.268

0.634(0.282,1.426)

21(38.89)

33(61.11)

0.424

0.771(0.408,1.458)

Nonsmoker

35(23.97)

111(76.03)

  

66(45.21)

80(54.79)

  

Drinking status

        

Drinker

14(17.72)

65(82.28)

0.238

0.653(0.321,1.329)

31(39.24)

48(60.76)

0.326

0.750(0.421,1.333)

Nondrinker

30(24.79)

91(75.21)

  

56(46.28)

65(53.72)

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