Table 3 Distribution frequencies of allele and genotype in patients and controls
SNPs | Cases n (%) | Controls n (%) | OR (95% CI) | P | |
|---|---|---|---|---|---|
HOTTIP rs1859168 | Â | Â | Â | Â | |
Genotype | AA | 44(22.00) | 69(34.50) | 1.000 | Â |
AC | 104(52.00) | 101(50.50) | 1.615(1.012–2.575) | 0.044 | |
CC | 52(26.00) | 30(15.00) | 2.718(1.511–4.890) | 0.001 | |
Dominant Model | AA | 44(22.00) | 69((34.50) | 1.000 | Â |
AC + CC | 156(78.00) | 131(65.50) | 1.867(1.198–2.911) | 0.005 | |
Recessive Model | AA + AC | 148(74.00) | 170(85.00) | 1.000 |  |
CC | 52((26.00) | 30(15.00) | 1.991(1.207,3.284) | 0.006 | |
Allele | A | 192(48.00) | 239(59.75) | 1.000 | Â |
C | 208(52.00) | 161(40.25) | 1.608(1.215–2.128) | 0.001 | |
MEG3 rs7158663 | Â | Â | Â | Â | |
Genotype | GG | 87(43.50) | 108(54.00) | 1.000 | Â |
GA | 76(38.00) | 71(35.50) | 1.329(0.865–2.041) | 0.194 | |
AA | 37(18.50) | 21(10.50) | 2.187(1.194–4.007) | 0.010 | |
Dominant Model | GG | 87(43.50) | 108(54.00) | 1.000 | Â |
GA + AA | 113((56.50) | 92(46.00) | 1.525(1.028–2.262) | 0.036 | |
Recessive Model | GG + GA | 163(81.50) | 179(89.50) | 1.000 |  |
AA | 37(18.50) | 21(10.50) | 1.935(1.088,3.442) | 0.023 | |
Allele | G Allele | 250(62.50) | 287(71.75) | 1.000 | Â |
A Allele | 150(37.50) | 113(28.25) | 1.524(1.132–2.051) | 0.005 | |